##master-date:Unknown-Date=
#format wiki
#language en

Here are wiki pages for the major projects I am working on.  This will serve as both a hyperlinked, dated electronic notebook and a rich, living document that will hopefully form the foundation for my dissertation.

[[TableOfContents(3)]]

== Projects Overview ==
Describes the directions of the projects and how they interact (or will eventually!) to form a cohesive research direction.

== Research Tools and Models ==

=== Automated Cardiac Measurement System ===
This page describes the design and implementation of various automation techniques applied to the measurement of heart function under controlled conditions (mainly hypoxia, also temperature control).

=== GAL4/UAS-RNAi System for Gene Knockdown in Adult Muscle ===
GFP and immunostaining to validate GAL4 drivers expressing in adult heart.  Validation of RNAi knockdown with the UAS system to prove feasibility of large, tissue-specific RNAi screen of heart function

=== Constraint-based Model of Central Metabolism in Hypoxic Drosophila Myocytes ===
Here I describe construction of the metabolic network, integration of experimental data, and model validation.

=== Integrated Drosophila Molecular Interaction Network ===

== Systems Analysis of Hypoxic Drosophila Heart ==
Brings together the network models (metabolic and protein/gene interaction) with the data (metabolomic, microarray, heart phenotypes) for hypothesis generation.  Systems analysis of the effects of genetic perturbations, aging, hypoxia adaptation, and drug combinations.

=== Aging ===

=== Hypoxia-adapted flies ===

== Miscellaneous ==

=== Fly ECG ===
Bioengineering Senior Design project

=== Heartbeat Reversal ===