== BENG 161A Bioreactor Engineering, Fall Quarter, 2007 ==

||'''Inst''' ||'''Day''' ||	'''Date''' ||'''#''' ||'''Topic''' ||'''Reading in Text''' ||'''HW Out''' ||'''HW Due''' ||
||AS ||Th ||9/27/2007 ||1 ||Cloning, expression, and manufacturing human recombinant erythropoietin ||1 || || ||
||JJ ||Tu ||10/2/2007 ||2 ||Chemical Reactions. Mass Action Kinetics. Allosteric Binding; e.g., hemoglobin. ||3.1,3.2 ||#1 || ||
||TA || || ||3 ||problem solving. || || || ||
||JJ ||Th ||10/4/2007 ||4 ||Michaelis-Menten, Rapid Equilibrium Assumption. Quasi-Steady State. ||3.3.1, 3.3.2 || || ||
||JJ ||Tu ||10/9/2007 ||5 ||Lineweaver-Burk plot. Enzyme Inhibition: Competitive, Non-competitive, Uncompetitive, Substrate Inhibition. ||3.3.3, 3.3.4 ||#2 ||#1 ||
||TA || || ||6 ||problem solving. Diffusion & Mass Transfer review. || || || ||
||JJ ||Th ||10/11/2007 ||7 ||Ex-Continuous Stirred Tank Reactor. Immobilized Enzymes. ||3.4.1 || || ||
||JJ ||Tu ||10/16/2007 ||8 ||Diffusional Limitations in Imobilized Enzyme Systems. Dahmkohler Number. ||3.4.2.1 || ||#2 ||
||TA || || ||9 ||problem solving. Sample problems. Quiz review. ||3.5, 3.6, 3.7 || || ||
||JJ ||Th ||10/18/2007 ||10 ||Effectiveness Factor. ||3.4.2.2 || || ||
|| ||Tu ||10/23/2007 ||11 ||Quiz #1 || || || ||
||TA || || ||12 ||problem solving. || || || ||
||HYM ||Th ||10/25/2007 ||13 ||Tour of Biogen Idec || || || ||
||HYM ||Tu ||10/30/2007 ||14 ||Cell Growth. Batch Reactors. Quantifying Cell Number and Mass. Monod Model. Yield & Maintenance Coefficients. ||6.1, 6.2, 6.3 ||#3 || ||
||TA || || ||15 ||problem solving. || || || ||
||HYM ||Th ||11/1/2007 ||16 ||Substrate-limited Growth. Optimization of Growth. Continuous Culture ||6.3.2, 6.4 || || ||
||HYM ||Tu ||11/6/2007 ||17 ||Scale-up, Operation and Control: Scale-up and its difficulties ||10.2 ||#4 ||#3 ||
||TA || || ||18 ||problem solving-MATLAB for systems of equations. || || || ||
||HYM ||Th ||11/8/2007 ||19 ||Bioreactor Instrumentation and Control, ||10.3, 10.4 || || ||
||ST ||Tu ||11/13/2007 ||20 ||Process design/flow and industrial practices for commodity scale chemical production || ||#5 ||#4 ||
||TA || || ||21 ||quiz review || || || ||
||ST ||Th ||11/15/2007 ||22 ||Medium selection, waste treatment and process economics || || || ||
||DC & AA ||Tu ||11/20/2007 ||23 ||Ideal Chemostat. Deviations from Ideality. Chemostat with Recycle. Multistage Chemostat. ||9.1-9.3.2 || ||#5 ||
|| || ||11/21/2007 ||24 ||no class || || || ||
|| ||Th ||11/22/2007 ||25 ||THANKSGIVING HOLIDAY || || || ||
|| ||Tu ||11/27/2007 ||26 ||Quiz #2 || || || ||
||TA || || ||27 ||Journal Review || || || ||
||RLS ||Th ||11/29/2007 ||28 ||Fed batch perfusion systems ||9.3.3, 9.3.4 ||#6 || ||
||DC & AA ||Tu ||12/4/2007 ||29 ||Product of animal cell culture. Sterilization. Mixed Cell Cultures. ||9.4, 10, 12 || || ||
||TA || || ||30 ||review || || || ||
||DC & AA ||Th ||12/6/2007 ||31 ||Genentech Tour || || ||#6 ||
|| ||Tu	||12/11/2007 || ||Final Exam (7:00pm - 10:00pm) || || || ||
 		Reading in Text:	 	Chapter # in Shuler & Kargi[[BR]]
		Inst:	 	Instructor Initials