Tutorial Title
Contents
Description
- This example makes use of the Electrophysiology Module's Equation Editor to create a 2D action potential propagation model on a mesh with heterogeneous properties. In essence, we will be making part of the mesh 'dead' electrically and note its influence on the shape of the propagating wave.
Start Continuity
- Launch the Continuity 6.3 Client
On the About Continuity 6.3 startup screen
check the specify module box under Use Modules:
Create Mesh
Select rectangular cartesian in the Global Coordinates: pop-up menu
Click OK to submit Coordinate Form
Choose Lagrange Basis Function→2D→Linear-Linear with 2 integration/collocation points for Xi 1 and Xi 2
Click Add
Choose Hermite Basis Function→2D→Cubic-Cubic with 2 integration/collocation points for Xi 1 and Xi 2
Click Add
Click OK to submit Basis Form
Click Import/Export/Graph button to open Continuity Table Manager
Continuity Table Manager→File→Open...
Select tab-delimited nodes file Upload new attachment "filename.xls"
Select Linear-Linear Lagrange 2*2 under Coordinate 1, Coordinate 2, and Coordinate 3
In the Field Vector 1 tab, select Linear-Linear Lagrange 2*2 under Field Variable 1, Field Variable 2, and Field Variable 3
In the Field Vector 2 tab, select Cubic-Cubic Hermite 2*2 under Field Variable 4
Click OK to submit Node Form
Click Import/Export/Graph button to open Continuity Table Manager
Continuity Table Manager→File→Open...
Select tab-delimited nodes file Upload new attachment "filename.xls"
Click OK to submit Element Form
Formulate XXXXX Problem
If the XXXX menu is not loaded, File→Load Module
Select xxxxxxxxCommands and click Load Module
In General Parameters tab
Enter output in the field next to Write output at nodes:
In the Fields definitions tab
Change the default Field Numbers from 1,2,3,4,5 to 1,2,2,3,4
Set Initial Intracellular Calcium Conc. to 0.1
Set Total Intracellular TnC Conc. to 70.0
Click OK to submit Edit Source Form
Biotransport→Select Solvers...
Select Radau in serial mode from ODE Integration pop-up menu
Select SuperLU in serial mode from Linear System Solver pop-up menu
Click surfaces radio button next to Normal to Xi
Click Render to display mesh surface
Compute and Render Solutions
Set Duration to 80 (ms)
Set Step Size to 0.5 (ms)
Under Solutions tab, select Display solution every 5 steps
click OK to start solving
When solution is complete, View→Change Renderer...
Click OpenMesh radio button
Click OK to change renderer
Set Number of Divisions: to 4
Set End Frame to 80
Set Max value: to 50
Click OK to view an animated color map of intracellular Calcium concentrations